Person suffering an anaphylactic reaction with swollen lips.

Anaphylaxis First Aid in Australia — Signs, Response and What to Have Ready

Reviewed: 27 April 2026

Anaphylaxis moves fast. Within minutes of exposure to a trigger, a mild reaction can escalate into a life-threatening emergency. Knowing the signs, knowing the steps, and having the right equipment ready before it happens is what saves lives — not trying to remember what to do in the moment.

This is the hub guide for anaphylaxis first aid in Australia — covering signs and symptoms, the correct ANZCOR response, equipment requirements for parents, schools, daycares and workplaces, and specific considerations for neurodiverse children and adults who may present or communicate differently during a reaction.

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What Australians Need to Know About Anaphylaxis

Anaphylaxis is a severe, potentially life-threatening allergic reaction. According to the Australasian Society of Clinical Immunology and Allergy, anaphylaxis affects approximately 1 in 3,000 Australians at some point in their lives, and rates of hospital admissions for anaphylaxis have been increasing over the past two decades.

The most common triggers in Australia include food allergens — particularly peanuts, tree nuts, shellfish, fish, milk, eggs, wheat, and sesame — as well as insect stings, medications, and latex. For children, food is the most common trigger. For adults, medications and insect stings are more prevalent.

What makes anaphylaxis particularly dangerous is its speed and unpredictability. A person who has previously experienced only mild allergic reactions can have a severe anaphylactic response to the same trigger. There is no reliable way to predict the severity of a reaction in advance.

Anaphylaxis Is Always a Medical Emergency Every anaphylactic reaction requires immediate treatment with adrenaline and a call to 000. Do not wait to see if the reaction settles. Do not give antihistamines as a substitute for adrenaline. Antihistamines do not treat anaphylaxis — they treat mild allergic reactions only.

Recognising Anaphylaxis — Signs and Symptoms

Symptoms can affect multiple body systems simultaneously and may develop within seconds or take up to 30 minutes after exposure. The Sydney Children's Hospitals Network notes that the following symptom combinations are key indicators of anaphylaxis:

Breathing Noisy breathing, wheeze, persistent cough, difficulty breathing, voice becoming hoarse or high-pitched
Circulation Pale or floppy appearance, loss of consciousness, sudden collapse, rapid or weak pulse
Skin Hives, welts, swelling of the face or lips, flushing, widespread redness
Digestive Persistent nausea or vomiting, abdominal cramping, diarrhoea
Other Sudden anxiety or sense of doom, swollen tongue, difficulty swallowing, tingling or numbness
In Young Children Sudden behaviour change, becoming floppy or pale, refusing to feed, persistent crying without clear cause
Mild Allergic Reaction vs Anaphylaxis — Know the Difference A mild allergic reaction may include localised hives, mild swelling, or a runny nose. Anaphylaxis involves two or more body systems OR any breathing or circulation symptoms — even without skin symptoms. When in doubt, treat as anaphylaxis and call 000.

First Aid Steps for Anaphylaxis — As per ANZCOR Guidelines

The Australian and New Zealand Committee on Resuscitation guidelines are clear. Follow these steps in order every time.

  1. Lay the person flat. Do not allow them to stand or walk. If breathing is difficult, allow them to sit up slightly — but keep them as flat as possible. If unconscious, place in the recovery position.
  2. Give adrenaline autoinjector. Administer the EpiPen or Neffy as per the person's ASCIA Action Plan if one is available. If no plan is available and anaphylaxis is suspected, use the autoinjector. Adrenaline is safe — the risk of not giving it is far greater than the risk of giving it unnecessarily.
  3. Call 000 immediately. Call even if the person appears to be improving. Symptoms can return after initial treatment — this is called a biphasic reaction and can occur hours later. All anaphylaxis requires emergency medical assessment.
  4. Give a second adrenaline dose if no improvement after 5 minutes. If a second autoinjector is available and symptoms are not improving, give a second dose. Note the time of each dose.
  5. Begin CPR if the person becomes unresponsive and is not breathing. Follow ANZCOR CPR guidelines — 30 compressions to 2 rescue breaths. Continue until emergency services arrive.
  6. Do not leave the person alone. Stay with them, keep them calm, and keep them flat until paramedics arrive.
Do NOT Do Any of the Following Do not give antihistamines instead of adrenaline · Do not allow the person to stand or walk · Do not leave them alone even if they appear to be recovering · Do not give asthma puffer as a substitute for adrenaline in anaphylaxis · Do not assume the reaction has passed because initial symptoms improve

What Every Australian Home, School and Workplace Needs

For Families

If anyone in your household has a known severe allergy, the Royal Children's Hospital Melbourne recommends keeping two adrenaline autoinjectors available at all times — one at home and one on the person or in their bag. Your kit should also contain a copy of the person's ASCIA Action Plan.

Both the Assurance Family First Aid Kit and the Family 4WD Outdoor Kit include a dedicated medication storage pouch — suitable for carrying an autoinjector and action plan alongside your first aid supplies.

Kits With Dedicated Medication Storage

Both of these kits include a personalised medication space — keeping the autoinjector with the kit so it's always accessible when you need it most.

Family First Aid Kit → Family 4WD Outdoor Kit →

For Schools and Daycares

Under Australian guidelines and the ASCIA Anaphylaxis Guidelines for Schools, early childhood services and schools must have an anaphylaxis management policy. This includes having adrenaline autoinjectors available for students with known allergies, a current ASCIA Action Plan for each at-risk student, and staff trained in anaphylaxis response.

Many states and territories also require schools to have a general-use EpiPen or Neffy for students who have not previously been diagnosed — because a child's first anaphylactic reaction may occur at school. Check your state's specific requirements with your state education department.

For Workplaces

Under Australian WHS legislation, employers must provide appropriate first aid for foreseeable emergencies. In workplaces where employees or visitors have known severe allergies, or where allergen exposure is a realistic risk — such as food service, manufacturing, or outdoor environments — having an adrenaline autoinjector as part of the first aid provision is appropriate. Always conduct a workplace risk assessment.

Anaphylaxis and Neurodiverse Children — What Parents and Carers Need to Know

Children with autism, ADHD, sensory processing differences, or communication differences may not be able to describe their symptoms clearly or in ways adults expect. A neurodiverse child experiencing anaphylaxis may appear to be having a meltdown, a sensory episode, or a behaviour change — rather than an allergic reaction.

Key signs to watch for in neurodiverse children that may indicate anaphylaxis rather than a behavioural response: sudden escalation in distress after eating or insect contact, change in skin colour, refusing to swallow or touching their throat, unusual vocalisation or change in breathing pattern, sudden limpness or loss of muscle tone.

The ASCIA Action Plan should include specific behavioural descriptors for the individual child — not just generic symptom lists. Work with the child's allergist and school to create a plan that reflects how that child specifically presents when unwell.

For broader guidance on first aid for neurodiverse children, see our complete guide for parents and carers →

The ASCIA Action Plan — What It Is and Why It Matters

An ASCIA Action Plan is a personalised emergency response document prepared by a medical practitioner for an individual with a known severe allergy. It specifies the person's triggers, their symptoms, which medication to give, and at what threshold — removing any ambiguity in an emergency.

Every person with a known severe allergy should have a current, signed ASCIA Action Plan. It should be kept with the adrenaline autoinjector — not in a separate location. For children, a copy should be held by the school or daycare, by carers, and at home.

EpiPen or Neffy? Australia now has two adrenaline autoinjector options — the traditional EpiPen (injected into the outer thigh) and Neffy (administered as a nasal spray). Both deliver adrenaline and both are approved by ASCIA for anaphylaxis treatment. The right choice depends on the individual — discuss with their allergist or GP. Read our full comparison: Neffy vs EpiPen — What Australian Parents and Carers Need to Know →

Frequently Asked Questions

What is the difference between a mild allergic reaction and anaphylaxis?
A mild allergic reaction typically involves localised symptoms — hives, mild swelling, runny nose, or watery eyes — affecting one body system. Anaphylaxis involves two or more body systems, or any symptoms affecting breathing or circulation. Any breathing difficulty, throat tightening, voice change, collapse, or pale and floppy appearance should be treated as anaphylaxis immediately.
Can you give antihistamines for anaphylaxis?
No. Antihistamines treat mild allergic reactions only. They do not work fast enough to treat anaphylaxis and should never be used as a substitute for adrenaline. If anaphylaxis is suspected, give the adrenaline autoinjector and call 000 immediately. Antihistamines may be given later as directed by medical staff — but not as the primary treatment.
What if I'm not sure whether to give the EpiPen?
If you are unsure whether to give adrenaline, give it. The ASCIA guidelines are clear — adrenaline is safe and the risk of not treating anaphylaxis far outweighs the risk of giving adrenaline unnecessarily. If in doubt, treat. Call 000 whether or not you give the autoinjector.
Do schools in Australia have to have an EpiPen?
Requirements vary by state and territory. Many Australian states require schools to have anaphylaxis management policies and adrenaline autoinjectors for students with known allergies. Some states also require a general-use autoinjector for undiagnosed reactions. Check with your state's education department for the specific requirements in your location.
How do I recognise anaphylaxis in a child who can't describe their symptoms?
In young children or children with communication differences, watch for sudden behaviour change after eating or insect contact, pallor or flushing, a floppy or limp body, refusal to swallow or touching the throat, unusual crying or distress that cannot be consoled, and any change in breathing. When in doubt, treat as anaphylaxis and call 000.

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About the Author

Samantha Kerr is the founder of Assurance First Aid Kits and a first aid trainer with 19 years of hands-on experience. Samantha has served with the Dubbo Volunteer Rescue Association and worked as a Patient Transport Officer in Outback NSW with AirMed — bringing real-world emergency experience to everything she teaches and every kit she builds.

References

Australian Resuscitation Council — ANZCOR Anaphylaxis Guidelines (resus.org.au)

Sydney Children's Hospitals Network — Anaphylaxis — Signs and Treatment (schn.health.nsw.gov.au)

Royal Children's Hospital Melbourne — Anaphylaxis (rch.org.au)

Better Health Channel — Anaphylaxis (betterhealth.vic.gov.au)

Australian Department of Health — Allergy and anaphylaxis in Australia (health.gov.au)

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